Is cognitive behavioural therapy an effective complement to antidepressants in adolescents? A meta-analysis
- Forfatter(e)
- Calati, R. Pedrini, L. Alighieri, S. Alvarez, M. I. Desideri, L. Durante, D. Favero, F. Iero, L. Magnani, G. Pericoli, V. Polmonari, A. Raggini, R. Raimondi, E. Riboni, V. Scaduto, M. C. Serretti, A. De Girolamo, G.
- År
- 2011
- Tidsskrift
- Acta Neuropsychiatrica
- Sider
- 263-271
- Kategori(er)
- Depresjon og nedstemthet (inkl. både vansker og lidelse) Angst og engstelighet (inkl. både vansker og lidelse)
- Tiltakstype(r)
- Kognitiv atferdsterapi, atferdsterapi og kognitiv terapiAntidepressiva
- Abstract
Objective: Evidence on effectiveness of combined treatments versus antidepressants alone in adolescents consists on a few studies in both major depressive and anxiety disorders. A meta-analysis of randomised 12-week follow-up studies in which antidepressant treatment was compared to combined treatment consisting of the same antidepressant with cognitive behavioural therapy has been performed.
Methods: Data were entered into the Cochrane Collaboration Review Manager software and were analysed within a random effect framework. A quality assessment has been performed through Jadad Scale.
Results: Higher global functioning at the Children's Global Assessment Scale was found in the combined treatment group (p < 0.0001) as well as higher improvement at the Clinical Global Impressions Improvement Scale (p = 0.04). No benefit of combined treatment was found on depressive symptomatology at the Children's Depression Rating Scale-Revised.
Conclusion: Combined treatment seems to be more effective than antidepressant alone on global functioning and general improvement in adolescents with major depressive and anxiety disorders:
(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).